ROLE SUMMARY:

Are you a highly motivated scientist driven to expand your laboratory skills to make scientific breakthroughs? Investigative Toxicology is looking to grow its world class team of leading researchers in Drug Safety Research & Development in Groton, CT. Our mission is to design and carry out investigative studies to derisk toxicity findings for molecules in preclinical and clinical development. These efforts include delivering robust high quality investigative toxicology data to support portfolio progression and/or mechanistic understanding of anticipated or realized nonclinical toxicology findings.

If you enjoy working in the lab, are naturally curious, and do not fear tackling experimental challenges, we want you to join us! The successful candidate will independently plan and execute screening and mechanistic in vitro assays, collect, analyze, and present data to project teams. Growth opportunities for highly motivated scientists in this position can expand beyond lab expertise to include contribution to peer-reviewed manuscripts, participation in delivering science & innovation (SIA) project proposals, engagement with external consortia and scientific presentations at national and global conferences.

ROLE RESPONSIBIILTIES:

• Provides hands-on technical expertise in specific areas such as safety screening and mechanistic target organ in vitro assays in the Global Discovery, Investigative & Translational Sciences (GDITS) organization.

• Performs cell culture of primary cells and cell lines, independently designs treatment paradigms, executes endpoint characterizations and sample collection to deliver robust, high-quality lab-based investigative toxicology data to support the development, validation, and implementation of in vitro safety assays.

• Analyzes, documents, and reports laboratory data in accordance with company standards and procedures.

• Participates in scientific evaluation of new technologies, assays and advancements that will enhance in vitro safety assessment to enable robust portfolio decisions.

• Effectively communicates and collaborates with Pfizer colleagues and global peers in DSRD, research units and partner lines, including preparation of laboratory reports and presentations.

• Performs all regulatory responsibilities in compliance with applicable regulatory standards.

QUALIFICATIONS:

• Bachelor’s degree in Toxicology, Molecular Biology, Pathobiology, Physiology, or related scientific field with at least 5+ years of relevant experience conducting laboratory research (advanced degree is a plus).

• Position requires hands-on application of aseptic laboratory techniques and technical in vitro culture expertise to test hypotheses, develop compelling data packages, and advance biological knowledge and drug development projects. Preferred: Experience with simple and complex in vitro models, primary cell isolation, phenotypic characterization using immunocytochemistry, high content imaging, and flow cytometry.

• Self-motivated, detail-oriented with excellent oral and written communication skills to effectively communicate within a team environment, enabling presentation and publication of scientific data and results.

• Strong interpersonal skills, able to take the initiative to lead projects and develop and execute a pre-determined plan.

• Should possess the ability to multi-task and align priorities with program objectives.

• Able to work in a fast-paced, rapidly changing environment, with solid decision-making skills to effectively troubleshoot and resolve moderately complex technical and scientific problems

  
Work Location Assignment: On Premise

The annual base salary for this position ranges from $74,900.00 to $124,800.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Research and Development