Summary

Dr. Putluri's lab is applying mass spectrometry technology to study metabolic profiling studies in cancer development and progression. The lab has established a robust research program in bladder cancer research. Particularly, has characterized metabolic alterations associated with smoking in bladder cancer, health disparity and defined a role xenobiotic metabolism in bladder cancer progression. The lab uses a variety of pre-clinical models that includes cancer cell lines, Organoid cultures, patient-derived xenografts (PDXs), and genetically engineered mouse models (GEMM). The lab is seeking a highly motivated Postdoctoral Associate, who is interested in translational tumor research.

Job Duties

• Collects, compiles, and analyzes data.
• Prepares and conducts laboratory research experiments.
• Collaborates with scientists out of the lab for multidisciplinary study.
• Develops new models and techniques to support the cancer-related research in the lab.
• Operates all the mass spectrometry instrumentation needed for the projects (training will be provided as needed).
• Documents experimental procedures in precise details.
• Collects and compiles imaging data.
• Assists in day-to-day operation of running scientific research lab.
• Attends lab meetings.
• Studies epigenetic mechanisms using in vitro, ex vivo, and in vivo models.
• Conducts independent research in the field of cancer metabolism.
• Focuses on cancer metabolism and tumorigenesis.
• Works in the lab that involves a combination of metabolomics, genomics, epigenomics, shRNA KD, CRISPR-gene editing approaches, over expression and a variety of model systems including cell line, organoids, mice and PDXs.
• Seeks external funding via grants applications/submissions.
• Conducts literature searches and summarizes information in an appropriate format for a particular study.
• Writes the IACUC, IRB and IBC reports and ensures these are kept updated.

Minimum Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

Preferred Qualifications

• Experiences in tissue culture and basic molecular biology techniques (e.g., PCR, DNA purification, Western blot, etc.).
• Experience with handling animal models that includes performing/maintaining therapeutic experiments using mouse models will be plus.
• Experience with LCMS or Cancer metabolism will be plus.