Chief of Staff, Commercialization

City of Hope

Duarte, CA

Job posting number: #7360224 (Ref:10035193)

Posted: June 15, 2026

Job Description

Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. Our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today.

City of Hope is undergoing a transformative evolution of its commercialization and strategic partnerships organization to accelerate the translation of scientific innovation into impactful solutions for patients. As part of this evolution, we are building an integrated, externally facing commercial engine across business development, venture creation, strategic partnerships, and innovation ecosystem development.

The Chief of Staff will serve as a strategic and operational partner to the Chief Commercialization Officer, supporting enterprise-wide initiatives, driving operational execution, enabling cross-functional alignment, and enhancing organizational effectiveness. This highly visible leadership role will help drive execution against key priorities, coordinate complex initiatives, and support leadership decision-making across a highly matrixed environment.

As a successful candidate, you will:

  • Partner closely with the Chief Commercialization Officer as a strategic advisor across the commercial organization
  • Drive execution of strategic priorities and transformation initiatives
  • Coordinate cross-functional efforts across business development, licensing, partnerships, and venture activities
  • Lead complex, enterprise-wide projects involving multiple stakeholders
  • Develop executive-level presentations, board materials, and strategic communications
  • Establish and manage operating rhythms, governance processes, and leadership forums
  • Track KPIs, milestones, and organizational performance metrics to ensure accountability
  • Identify operational gaps, risks, and opportunities, and drive solutions proactively
  • Serve as a key liaison across leadership, scientific stakeholders, and external partners
  • Support organizational design, process optimization, and scaling initiatives

Your qualifications should include:

  • Bachelor’s degree required; MBA or other advanced degree preferred
  • 10+ years of experience supporting C-suite leadership in commercialization, strategy, R&D, or related functions
  • 7+ years of experience leading senior teams and driving complex initiatives
  • Executive-level communication skills with the ability to develop high-impact presentations and materials
  • Proven ability to manage cross-functional projects in highly matrixed environments
  • Strong organizational, strategic thinking, and project management capabilities
  • Demonstrated ability to influence senior stakeholders and drive alignment
  • Experience in process improvement, operational scaling, and performance tracking
  • High level of discretion, business acumen, and interpersonal effectiveness
  • Financial acumen, including experience with budgets and business modeling

City of Hope employees’ pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

Salary / Pay Rate Information:
Pay Rate: $100.23 - $167.38 / hour

The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.



City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.


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More Info

Job posting number:#7360224 (Ref:10035193)
Application Deadline:Open Until Filled
Employer Location:City of Hope
Duarte,California
United States
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